One Drawing From 1588 Matched a Pomegranate to Your Jaw
An old scholar in Naples set the fruit beside a set of teeth. Four centuries later, two dental teams put his hunch to the test.
Run your tongue along your back teeth after lunch. Feel that soft, fuzzy coat? That is plaque. It is a thin film of live bacteria, and it starts to build back within hours of brushing.
Left alone, that film creeps down to the gum line. The gums get red and puffy. They may bleed a bit when you brush. Most of the time it does not hurt, so lots of people have no idea it is going on. Gum trouble is one of the most common problems in grown adults, and it gets more common with age.
Dentists have a strong drug rinse for it, and it works well. But used for weeks on end, it can stain your teeth brown and change how food tastes. So most people use it only for a short stretch.
Now here is the odd part. A fruit in your store right now was drawn next to a human jaw more than four hundred years ago. And two dental teams have since tested it against that drug rinse...
Let me explain...
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The Man Who Read Plants Like Faces
Giambattista della Porta was born in Naples around 1535. He spent his life poking at the world. Over the years he wrote about lenses, about tricks of the eye, and about plants. In 1588 he put out a book called Phytognomonica. The long name means, more or less, "reading the faces of plants."
The book rests on an old folk idea called the Doctrine of Signatures. If a plant looks like a part of you, the idea goes, nature made it to help that part. Della Porta filled his pages with woodcut pictures. A plant sits on top, and a body part sits below.
One page shows a pomegranate split open. Under it sits a human jaw, teeth and all. Put the two side by side and you see what he saw. Rows of glossy red seeds, packed tight in their pale walls, line up like teeth in a gum.
The Wellcome Collection in London keeps a 1588 copy of the book. It also holds a hand-painted copy of that same picture, made in 1906.
For a long time, that page was just a charming guess. A shape is not a cure. So was della Porta simply lucky?
What the Rind Holds
He was closer than he knew. The thick rind of a pomegranate, and the pale walls inside, are packed with tannins. These are the compounds that make an unripe fruit feel dry and puckery in your mouth. In the pomegranate, the main ones are called punicalagins. You can say the word once and forget it.
In lab dishes, these tannins do two things to mouth bacteria. They kill some of them outright. And they make it hard for others to build the sticky glue they use to grab onto a tooth.
That glue is the whole game. Bacteria that can't hold on get washed off by your spit. Those that can hold on pile up, layer by layer, into plaque.
The fruit also carries ellagic acid, which may help calm puffy gums. That part is less proven, so hold it loosely...
Study: In Brazil, sixty young people with braces each swished a pomegranate rinse, a drug rinse, or plain water for one minute. The pomegranate rinse did about as well as the drug at cutting plaque bacteria, and far better than water.
When a Lab Tested the Old Drawing
In 2006, a medical school team in Juazeiro do Norte, a city in northeast Brazil, ran a simple test. They signed up 60 young people with braces, ages 9 to 25. Braces trap plaque, so they make a good test bed. Nobody brushed for a full day first.
Each person got one rinse, for one minute. One group used pomegranate extract. A second got the drug rinse. Plain water went to the third group. The team counted the plaque bacteria before and after.
Pomegranate cut the count by 84 percent. The drug rinse cut it by 79. Plain water cut it by just 11. The results ran in the Journal of Herbal Pharmacotherapy.
That does not mean the fruit beat the drug. The two were close, and the groups did not start out even. Put fairly: one rinse of pomegranate did about as well as the drug, and far better than water.
A Second Look, Three Weeks Long
A one-minute test is a snapshot. So a dental college in Thiruvananthapuram, India, ran a longer one. Sixty adults with mild gum swelling rinsed twice a day for 21 days. Half used a rinse made from pomegranate peel. The rest used the drug rinse. Neither they nor the testers knew who got which.
Both groups ended with less plaque and calmer gums than they had at the start. The results ran in the journal Cureus in 2025.
Now the honest part. Both trials were small. Each one used strong extracts, mostly from the rind, held in the mouth as a rinse. The first one tested young people with braces, not adults in their 60s. And no trial has yet shown that eating the seeds keeps gums healthy over months or years.
So the fruit is not a swap for your toothbrush, your floss, or your dentist. Think of it as a good food with an old story and some early lab support behind it.
Three Things Worth Knowing At The Store
01
Pick the Heavy One
A good pomegranate feels heavy for its size. That weight is juice. Look for tight, leathery skin and a slightly squared-off shape. Skip any with soft spots or deep cracks.
02
Keep It Cold
A whole pomegranate keeps a week or two on the counter, and up to two months in the fridge. Once you free the seeds, keep them in a covered bowl in the fridge and eat them within five days.
03
Eat It With a Meal
Mouth bacteria feed on sugar, and the fruit has some. A bowl at lunch gives them one short meal. Picking at seeds all afternoon gives them a feast. Eat your share in one sitting.
HERE'S WHAT I'D DO THIS WEEK
Buy one pomegranate this week. They are in season now through about January.
Eat about half a cup of seeds a day with a meal, on a salad, in a grain bowl, or straight from the bowl. Chew them slowly.
Keep brushing twice a day and flossing. The fruit adds to that habit. It does not take its place.
Talk to your doctor first if you take a blood thinner or another daily medicine. Pomegranate may change how some drugs work.
Della Porta had no microscope and no lab. He had a split fruit, a sharp eye, and an old idea about shapes.
The idea itself was wrong. But the fruit he picked held something worth a closer look, right where he was looking.
Pick up one pomegranate this week. Eat half a cup of the seeds with lunch each day, and keep your toothbrush close.

